Vikings-Saints - Kevin O’Connell looks to improve to 3-1 with a win in London
Titans-Colts - Which AFC South team saves their season?
Seahawks-Lions - Could Seattle drop to 1-3 in the NFC West by losing to Jared Goff again?
Bears-Giants - Will Bears or Giants be an unreasonable 3-1 by winning this game?
Jaguars-Eagles - Can Trevor Lawrence be the one to stop Jalen Hurts?
Bills-Ravens - The winner will be 3-1 and be atop the AFC, and the winning QB could be ahead in the MVP race
Cardinals-Panthers - Will Arizona be able to rebound this season?
Chiefs-Bucs (SNF) Tom Brady against Patrick Mahomes, will it be better than Brady vs Rodgers?