Obvious playoff implications on the line. With Kyle Orton having helped the Bills go 3-1 since taking over for E.J. Manuel, it should be interesting to see this one play out up in Buffalo. Kansas City's passing attack is pretty dismal, but they defend the pass extremely well.
Another big matchup with postseason implications on the line. Miami is growing into a quality team coming off of a 37-0 trouncing of early season starlet San Diego. Detroit's coming off of a bye week allowing Calvin Johnson to heal up. With Detroit's defensive line, they could be on their way to a first division title since 1993.
* - to be played at Wembley Stadium, London, England
Well, you've got the London angle. You've got Tony Romo who might be able to play, or at least start, despite broken bones in his back. And you've got what looks on paper to be an easy win for Dallas. If Jacksonville can stick in this through halftime, this could be fun.
Two teams underperforming preseason expectations needing a win to right the ship in November? Something tells me motivation won't be lacking in this one...
Meh. Steer clear.
I don't know if this is the game for the Jets to stop the slide, but it could be fun simply for chaos' sake.
Falcons (2-6) at Buccaneers (1-7) - game page
Worst game of the early stretch. Cross your fingers for Steven Jackson who is clearly at the end of a stellar career. This is draft order fodder though.